The buildup of amyloid plaque in the brain is strongly associated with Alzheimer’s disease. Identifying early symptoms could therefore be the key to effective treatment. “Alzheimer’s disease is a neurodegenerative disease, so at the end you can see a lot of loss of neurons,” says Wen-Chin “Brian” Huang, PhD. “At this stage, it would be difficult to cure the symptoms. It is really essential to understand which circuits and regions show neural dysfunction early in the disease. This in turn will facilitate the development of effective therapies. Here are five signs of amyloid buildup, according to experts. Read on and to ensure your health and the health of others, don’t miss these Sure signs you’ve already had COVID.
According to doctors, mild cognitive impairment (MCI) is one of the earliest and most common signs of Alzheimer’s disease. “The most common sign is a problem with memory, and it’s usually episodic, which means it’s hard to remember events in your life, past and present,” explains Dr. David Caplanprofessor of neurology at Harvard Medical School.
Unexplained personality changes are another early sign of neurological issues, especially depression, apathy, self-centered behavior, and rigidity. “Behavioral changes are very common and affect more than 95% of people with dementia,” says Ganesh Gopalakrishna, MD. These symptoms may be present 10 to 15 years before memory loss occurs.
Experts say unexplained paranoia could be a sign of dementia or Alzheimer’s. “Many patients suffer from depression, paranoia or hallucinations,” says Dr. Gopalakrishna. “It can be enough to make a person feel unsafe, even in their own home. The first step in these situations is to provide a safe environment, limiting the risk of accidental or intentional injury to oneself. or to others.”
Unexplained financial problems – for example, forgetting to pay bills, drastic changes in credit scores – could be a sign of Alzheimer’s disease. “Currently, there is no effective treatment to delay or reverse the symptoms of dementia,” says Lauren Hersch Nicholas, PhD, associate professor in the Department of Health Policy and Management at the Bloomberg School. “However, earlier screening and detection, combined with information about the risk of irreversible financial events, such as foreclosure and repossession, are important to protect the financial well-being of the patient and their family. We We don’t see the same pattern with others. Dementia was the only medical condition for which we observed consistent financial symptoms, particularly the long period of deterioration in outcomes before clinical recognition. Our study is the first to provide evidence large-scale quantitative studies of the medical adage that the first place to look for dementia is in the checkbook.”
Hearing loss isn’t just associated with dementia, it could be a cause of the disease, experts say. “Hearing loss can make the brain work harder, forcing it to strain to hear and fill in the gaps,” according to Frank Lin, PhD. “This comes at the expense of other thought and memory systems. Another possibility: hearing loss causes the aging brain to shrink more rapidly. A third possibility is that hearing loss leads people to be less socially engaged, which which is extremely important for staying intellectually stimulated. . If you can’t hear very well, you might not get out as much, so the brain is less engaged and active.”
Ferozan Mast is a science, health and wellness writer passionate about making science and research-based information accessible to the general public. Learn more about Ferozan